Malaz AlBasha*(1)
(1). Department of Organic Chemistry, Faculty of Science, University of Aleppo, Aleppo, Syria.
(*Corresponding author: Dr. Malaz Albasha. E-Mail: malazalbasha9@gmail.com).
Received: 29/01/2019 Accepted: 12/04/2019
Abstract
The present study was conducted between the beginning of May to the end of August in 2017, where the plant was collected from the fields of Deir Al-Zour. The active componentsof theaerial parts and roots of Achillea FalcataL. were extracted using different solventsofmethanol 70%, ethanol 80%, methanol 99.9%, ethanol 96%, chloroform 99.8% and hexane 98.5%. The ethanol 80% extracts achieved the highest extraction in both aerial parts and roots. Qualitative phytochemical screening ofcarbohydrates,tannins and saponin in previous extracts was done where the carbohydrates was presented in high concentrations in Achillea Falcata L. The content of flavonoids was determined and it was found that ethanol 80% extracts achieved the highest percentage in both aerial parts (59.21mg/g) and roots (25.26mg/g) of Achillea Falcata L. The total antioxidant activity was estimated by the DPPH radical scavenging activity and it was found that methanol 70% extracts achieved the highest percentage in both aerial parts (78.42%) and roots (64.83%) extracts of Achillea Falcata L. in comparison with other studied extracts. One compound was isolated and studied from Achillea Falcata L. extract which is Luteoline, by using spectroscopic and chromatographic methods (UV, IR and HPLC).
Key words: Antioxidant activity, Achillea falcate L., Active components, Ethanol extract, Methanol extract, Free radical DPPH.