{"id":11834,"date":"2026-10-31T15:55:00","date_gmt":"2026-10-31T15:55:00","guid":{"rendered":"https:\/\/agri-research-journal.net\/SjarEn\/?p=11834"},"modified":"2026-10-31T15:55:00","modified_gmt":"2026-10-31T15:55:00","slug":"efficacy-of-orange-peel-extract-colistin-azithromycin-gentamicin-and-doxycycline-against-escherichia-coli-isolated-from-broiler-chickens","status":"publish","type":"post","link":"https:\/\/agri-research-journal.net\/SjarEn\/?p=11834","title":{"rendered":"Efficacy of Orange peel extract, Colistin, Azithromycin, Gentamicin, and Doxycycline against Escherichia coli isolated from broiler chickens"},"content":{"rendered":"<p style=\"text-align: center;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>Alaa Afif<sup>1*<\/sup>, Ali Nisafi<sup>2<\/sup> and Abdel Nasser Al Omar<sup>3<\/sup><\/strong><\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">1 Tartous Research Center, General Commission for Scientific Agricultural Research, Syria.<\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\">2 Department of Animal Production, Faculty of Agriculture, Lattakia University, Lattakia, Syria.<\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\">3 Hama Research Center, General Commission for Scientific Agricultural Research. <\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\">(*Corresponding author: Alaa Afif, Email: <a href=\"mailto:alaa.afef88@gmail.com\">alaa.afef88@gmail.com<\/a> Mob: 0982179887).<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-family: 'times new roman', times, serif;\">Received: 8\/ 3\/ 2026\u00a0 \u00a0 \u00a0 Accepted: 2\/ 6\/ 2026<\/span><\/p>\n<p><span style=\"font-family: 'Times New Roman', Times; font-size: 17px;\"><strong>Abstract:\u00a0<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'Times New Roman', Times; font-size: 17px;\">The research was conducted on (10) farms in Tartous Governorate to isolate and confirm Escherichia coli infection and to study the effectiveness of some antibiotics used in its treatment, comparing them with two orange peel extracts (aqueous and alcoholic) in order to find natural alternatives to antibiotics and reduce their side effects. Suspected infected birds were collected between November 13, 2023, and July 9, 2024, from different areas in Tartous. Clinical symptoms were recorded, and pathological examinations were performed. Samples were cultured in nutrient broth and incubated at 37\u00b0C for 24 hours, then cultured on specific media to identify and isolate the bacteria. Susceptibility tests were performed for colistin, gentamicin, azithromycin, and doxycycline, and the results were compared with those of the aqueous and alcoholic orange peel extracts. The results showed the superiority of the alcoholic and aqueous orange extracts over commercial antibiotics. The average inhibition diameters were 10.667 mm for the alcoholic extract and 8.367 mm for the aqueous extract, compared to 9.667 mm and 8.200 mm for the antibiotics colistin, gentamicin, azithromycin, and doxycycline, respectively. This indicates the promising efficacy of these extracts.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\"><strong>Keywords:<\/strong> Escherichia coli, chicken, orange peels, antibiotics.<\/span><\/p>\n<p><strong><span style=\"font-family: 'times new roman', times, serif;\">\u00a0Full paper in Arabic: <a href=\"http:\/\/agri-research-journal.net\/SjarEn\/wp-content\/uploads\/v13n5p21-1.pdf\">PDF<\/a><\/span><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Alaa Afif1*, Ali Nisafi2 and Abdel Nasser Al Omar3 1 Tartous Research Center, General Commission for Scientific Agricultural Research, Syria. 2 Department of Animal Production, Faculty of Agriculture, Lattakia University, Lattakia, Syria. 3 Hama Research Center, General Commission for Scientific &hellip; <a href=\"https:\/\/agri-research-journal.net\/SjarEn\/?p=11834\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-11834","post","type-post","status-publish","format-standard","hentry","category-sjar"],"_links":{"self":[{"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=\/wp\/v2\/posts\/11834","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=11834"}],"version-history":[{"count":1,"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=\/wp\/v2\/posts\/11834\/revisions"}],"predecessor-version":[{"id":11837,"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=\/wp\/v2\/posts\/11834\/revisions\/11837"}],"wp:attachment":[{"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=11834"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=11834"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=11834"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}