{"id":11119,"date":"2026-04-29T09:25:01","date_gmt":"2026-04-29T09:25:01","guid":{"rendered":"https:\/\/agri-research-journal.net\/SjarEn\/?p=11119"},"modified":"2026-04-29T09:25:01","modified_gmt":"2026-04-29T09:25:01","slug":"modeling-the-process-of-alcoholic-fermentation-using-saccharomyces-cerevisiae-in-matlab-simulink","status":"publish","type":"post","link":"https:\/\/agri-research-journal.net\/SjarEn\/?p=11119","title":{"rendered":"Modeling the process of alcoholic fermentation using Saccharomyces cerevisiae in MATLAB\/Simulink"},"content":{"rendered":"<p style=\"text-align: center;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>Yahia Esmail<\/strong><strong><sup>1*<\/sup>, Ramez Mohammad<sup>1<\/sup> and Oulfat Jolaha<sup>2<\/sup><\/strong><\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">1 Department of Food Science, Lattakia University, Syria. <\/span><br \/><span style=\"font-family: 'times new roman', times, serif;\">2 Department of Computer Engineering and Automatic Control, Lattakia University, Syria. <\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">(*Corresponding author: Yahia Esmail, Email: <a href=\"mailto:yahia.esmail@tishreen.edu.sy\">yahia.esmail@tishreen.edu.sy<\/a>, Tel: +963 936 094505).<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>Received: 3\/ 3\/ 2025\u00a0 \u00a0 \u00a0 \u00a0Accepted: 5\/ 7\/ 2025<\/strong> <\/span><\/p>\n<p><span style=\"font-family: 'Times New Roman', Times; font-size: 17px;\"><strong>Abstract<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'Times New Roman', Times; font-size: 17px;\">In this study, filtered and purified grape juice was fermented at 25\u2103, after the juice was inoculated with instant dry yeast Saccharomyces cerevisiae ATCC\u00ae 2601&#x2122; and the fermentation process took 10 days, a sample was taken every 24 hours to measure the total sugars concentration, biomass and ethanol concentration formed during fermentation. The initial conditions were set as follows: initial sugars concentration S_0=200 \u00b1 0.059g\/l, initial alcohol concentration P_0=0g\/l, initial yeast concentration X_0=1.5g\/l, it was observed that 12.66 \u00b1 0.071g of sugars were consumed after one day of fermentation to produce 10.52 \u00b1 0.22g of ethanol, which represents 83.10% of the consumed sugars, and the biomass increased by 0.66 \u00b1 0.273g, which represents 5.21% of the consumed sugars. The consumption of the substrate continues with the increase in the fermentation period, so that the total consumed sugars reached about 95.74% on the tenth day of fermentation, i.e. at a rate of 191.48 \u00b1 1.291 g, and the maximum alcohol concentration on the tenth day also reached 120.1 \u00b1 0.04g\/l. As for the biomass, the maximum concentration of biomass was X_max=15.39 \u00b1 0.04g\/l on the tenth day of fermentation, and the growth rate of yeast cells was \u03bc_max=0.674\/l. The process of biomass formation, substrate consumption, and alcohol production were modeled according to three special equations as a function of time, which were solved by Runge-Kutta and Euler methods, where the results of the solution by Euler method outperformed the results of the Runge-Kutta method in the measurements of biomass, substrate, and ethanol due to the low value of the coefficient of Determination R^2, the mean absolute error MAE, and the mean square error MSE, where the values reached:<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\"><strong>Keywords:<\/strong> Biomass, Substrate, Differential Equations, Runge-Kutta, Euler.<\/span><\/p>\n<p><strong><span style=\"font-family: 'times new roman', times, serif;\">\u00a0Full paper in Arabic: <a href=\"http:\/\/agri-research-journal.net\/SjarEn\/wp-content\/uploads\/v13n2p39.pdf\">PDF<\/a><\/span><\/strong><\/p>\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Yahia Esmail1*, Ramez Mohammad1 and Oulfat Jolaha2 1 Department of Food Science, Lattakia University, Syria. 2 Department of Computer Engineering and Automatic Control, Lattakia University, Syria. (*Corresponding author: Yahia Esmail, Email: yahia.esmail@tishreen.edu.sy, Tel: +963 936 094505). Received: 3\/ 3\/ 2025\u00a0 &hellip; <a href=\"https:\/\/agri-research-journal.net\/SjarEn\/?p=11119\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[413],"tags":[287,1321,1323,1322,1320],"class_list":["post-11119","post","type-post","status-publish","format-standard","hentry","category-biotechnology","tag-biomass","tag-differential-equations","tag-euler","tag-runge-kutta","tag-substrate"],"_links":{"self":[{"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=\/wp\/v2\/posts\/11119","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=11119"}],"version-history":[{"count":1,"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=\/wp\/v2\/posts\/11119\/revisions"}],"predecessor-version":[{"id":11121,"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=\/wp\/v2\/posts\/11119\/revisions\/11121"}],"wp:attachment":[{"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=11119"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=11119"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/agri-research-journal.net\/SjarEn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=11119"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}